British Air Force Typhoon jets have operated alongside French aircraft in a coordinated attack targeting an hidden munitions depot in Syria used by the IS group, as stated by the UK's MoD.
The location, located using reconnaissance, was believed to be storing arms and explosives, the statement said, and was positioned in hills just to the north of Palmyra in central Syria.
"The RAF jets employed precision-guided Paveway IV munitions to hit a number of entry passages providing entry to the facility... preliminary assessments suggest the target was engaged successfully," officials stated.
There was no indication of any civilian casualties in the strike on Saturday evening and all the aircraft made a safe return, the defence officials confirmed.
The Typhoon FGR4s were backed up by a Voyager refuelling tanker.
Daesh - also known as the so-called Islamic State - imposed militant control over large swathes of Syria and Iraq prior to its 2019 collapse.
"This operation shows British leadership, and resolve to work closely with our allies, to stamp out any re-emergence of Daesh and their harmful and extremist ideologies in the area," the British Defence Secretary John Healey stated.
RAF aircraft have carried out surveillance missions over Syrian airspace to "deter any efforts to regroup" of IS following its defeat at the climactic battle in Baghuz in 2019, the MoD reported.
"I must thank the personnel of our armed forces who took part in this mission for their expertise and their valour," the Defence Secretary commented. "Including them were a great many British personnel stationed over the holidays. This mission, to remove terrorist threats who endanger our security, demonstrates how British military are prepared to act, continuously, protecting the UK within its borders and strong abroad."
In December, the United States armed forces carried out what it called a "large-scale strike" against Daesh sites in the country, after an attack resulted in the deaths of two US troops and a civilian linguist in Palmyra.
The U.N. says Daesh still maintains roughly 5-7 thousand combatants in Syria and Iraq.